Protein or peptide name:KdpF
Chromosome:Mycobacterium_bovis_AF2122/97
Protein or peptide start site:1152395
Protein or peptide end site:1152487
ncRNA start site:1152395
ncRNA end site:1152487
Genome Browser:NA
Protein or peptide sequence:MTTVDNIVGLVIAVALMAFLFAALLFPEKF
Protein or peptide length:30aa
ncRNA type:ncRNA
ncRNA name:kdpF
Entrez ID:3205056
Experimental species:Mycobacterium tuberculosis
Experimental techniques:Western blotting
Experimental sample (cell line and/or tissue):Mycobacterium bovis BCG
Description:The 30 amino-acid-long KdpF peptide, which is co-transcribed with kdpABC genes and regulated by the KdpDE two-component system, is supposed to stabilize the KdpABC potassium transporter complex but may also exhibit unsuspected regulatory function (s) towards the KdpD sensor kinase.
Subcellular location:membrane
Function:KdpF overexpression reduces intramacrophage growth which may result from alteration of the mycobacterial cell wall.
Title of paper:Overexpression of the KdpF membrane peptide in Mycobacterium bovis BCG results in reduced intramacrophage growth and altered cording morphology
PMID:23577107
Year of publication:2013