Protein or peptide name: | KdpF |
Chromosome: | Mycobacterium_bovis_AF2122/97 |
Protein or peptide start site: | 1152395 |
Protein or peptide end site: | 1152487 |
ncRNA start site: | 1152395 |
ncRNA end site: | 1152487 |
Genome Browser: | NA |
Protein or peptide sequence: | MTTVDNIVGLVIAVALMAFLFAALLFPEKF |
Protein or peptide length: | 30aa |
ncRNA type: | ncRNA |
ncRNA name: | kdpF |
Entrez ID: | 3205056 |
Experimental species: | Mycobacterium tuberculosis |
Experimental techniques: | Western blotting |
Experimental sample (cell line and/or tissue): | Mycobacterium bovis BCG |
Description: | The 30 amino-acid-long KdpF peptide, which is co-transcribed with kdpABC genes and regulated by the KdpDE two-component system, is supposed to stabilize the KdpABC potassium transporter complex but may also exhibit unsuspected regulatory function (s) towards the KdpD sensor kinase. |
Subcellular location: | membrane |
Function: | KdpF overexpression reduces intramacrophage growth which may result from alteration of the mycobacterial cell wall. |
Title of paper: | Overexpression of the KdpF membrane peptide in Mycobacterium bovis BCG results in reduced intramacrophage growth and altered cording morphology |
PMID: | 23577107 |
Year of publication: | 2013 |